99 Art Center was created in 2003 to expose talented Taiwanese artists. Right in the heart of the eclectic and hectic Renai-Tughua neighborhood, the gallery sits within spitting distance of bustling with life Dunhua road with restaurants, clothing shops and western bars. It champions artists who create distinctive, abstract images.

In 2008 the gallery opened a branch in Shanghai to promote local, Taiwanese fine arts and to promote artistic exchange. 99 Art Center's exhibitions are typically solo exhibitions that change twice a month. The gallery represents many artists such as: Eddie Huang, Li Suntta Alexandre, Yang Yan-Nang, Hsu Ming Hsiung, Wu Ting Hsien and many others.